Description

Liposomeproducts

Clodronateliposomes:

ArtificialspheresconsistingofconcentricphospholipidbilayersencapsulatinganaqueousPBS(phosphatebufferedsaline)solutioncontainingclodronate.Liposomesareparticles,sizedatamax.of3micron.TheyareformingasuspensioninPBSandwilltendtoprecipitateuponstorage,formingapelletonthebottomofthetubeorflask.Thesuspensionshouldbeshakenbeforeadministrationtolaboratoryanimalsinordertorecoverthehomogeneoussuspension.

PBS(control)liposomes:

Controlliposomesdonotcontainclodronate.ContainingPBSonly,theycanbeusedforcontrolexperiments,inordertofindoutwhethertheeffectsobservedafterinjectionofclodronateliposomesareduetomacrophagedepletionexclusively.